Endothelio- and cardioprotective effects of vitamin в6 and folic acid in modelling methionine-induced hyperhomocysteinemia

نویسندگان

چکیده

The endotelio- and cardioprotective effects of vitamin B6 (2 mg/kg) folic acid (0.2 upon modeling methionine-induced hyperhomocysteinemia via methionine intragastric administration at a dose 3 g/kg were studied. It was shown that the combined use allows on background significant reduction in homocysteine concentrations normalizing endothelial dysfunction coefficient parameters maximum left ventricular pressure response to intravenous adrenaline. research partially supported by grant President Russian Federation №MD-4711.2015.7.

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ژورنال

عنوان ژورنال: Research results in pharmacology

سال: 2023

ISSN: ['2658-381X']

DOI: https://doi.org/10.18413/2313-8971-2016-2-1-16-19